Page 16 - Eshre 2018
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Adverse effect of radiotherapy to uterus
Miscarriage
Percent 5/8
60
50
40
30
20
10
Premature delivery
6/16
80
60 40 20 0
8/44
TBI Cyclophos
Expected
0 TBI
4/56
Cyclophos Expected
Sanders et al 1996 Blood 87, 3045
TBI and uterine volume
50 40 30 20 10
0
38.9 (26.8 ‐ 54)
16.5 (8.3 ‐ 27.4)
TBI D3‐5
*
6.5 (1.7 ‐ 12.7)
*
TBI No HRT
Chemo/Controls D3‐5
Bath LE et al BJOG 1999
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Uterine volume (mls) [median (range)]
