Page 97 - PCC10

Endometrial Regeneration
Day 13 Day 3
Day 19
Fu n c t i o n a l l a y e r
Basal layer Myometrium
Page 91 of 135
www.youtube.com/watch?v=l_wX285vrrU&t=183s
Schering‐Plough
Prianishnikov, Contraception 1978 Padykula et al., Biol Reproduction 1984
Remarkable regenerative capacity
500 timesor ....forever
The concept of the niche
A specific microenvironment in which adult stem cells regulate their division and cellfate decisions
Schofield,Blood Cells1978
In humans, the endometrial stem cell niche is located at the endothelium of the spiral arterioles in the basal layer
M a r u k a m i e t a l . , En d o c r i n o l o g y 2 0 1 4
PRECONGRESS COURSE 10 I BARCELONA, SPAIN – 1 JULY 2018 97