Page 127 - PCC10

Adipose derived stem cell
• Liposuction
• Enzym digestion
• Centrifugation
• SVF (stromal Vascular fraction)
IFD‐Grand Solutions 2017‐Sheikh/CVR
Mechanisms of action
1 Differentiation to other cell type
2 Paracrin activity promoting tissue regeneration
SDF‐1 HGF IGF‐1
IL‐11 PGE2 TSG‐6
VEGF‐A PDGF ANG1
3 Transfer in microtubuli
Ca2+ Mg 2+ RNAs
IFD‐Grand Solutions 2017‐Sheikh/CVR
Tagret cell
4 Transfer of molecules from exosomes/microvesicles
Tagret cell
Page 121 of 135
PRECONGRESS COURSE 10 I BARCELONA, SPAIN – 1 JULY 2018 127