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Fecundity per Ovulated Patient
Legro et al, JCEM 2015
Is Pretreatment Worth it?: Post Hoc Comparison with PPCOSII Age/BMI Matched Women (N = 201)
PPCOS II
OWL‐PCOS
Outcome
Clomiphene
OCP
Lifestyle
Combined
Ovulation Rate
Cumulative after 4
44.7%
46.1%
60.3%
67.1%
cycles
Relative Rate (95% CI)
Compared to PPCOSII
‐‐
N.S.
RR=1.4 (1.1, 1.7) p=0.005
RR=1.5 (1.2, 1.8) p<.0001
Live Birth Rate per patient
Cumulative after 4
10.4%
10.2%
26.0%
24.0%
cycles
Relative Rate (95% CI) Compared to
RR=2.5 (1.3, 4.6); p=0.004
RR=2.3 (1.2, 4.3) p=0.01
PPCOSII
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