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Why no consensus?
• Technicalissues
Different ultrasound machine Different AMH assays
• Populationissues
Patient populations
Control populations+++ (PCOM-free?)
If using PCOM-free controls:
ROC ANALYSIS AFTER PRELIMINARY STEP BY CLUSTER ANALYSIS
Follicles/ovary
sens = 81% spe = 92%
19 foll/ov
AMH
sens = 92% spe = 97%
35 pMol/L (5 ng/ml)
14
Zone sous la courbe
iraVariable(s) de résultats tests: FOLL 2D MOY (2-(29)
ZooneZne
Erreur Std.a
Signif. asympitsysyapeuqopauqomtotique b
Intervalle de confiance 95% asymptotique
Borne inférieure
Borne supérieure
,949
,017,170710
,000,0
,915,159519
,982,829289
Zone sous la courbe
Variable(s) de résultats tests: AMH
iraV
Zone
enoZ
a Erreur Std. a
Signif. asymptotique b
b
Intervalle de confiance 95% asymptotique
Borne inférieure
Borne supérieure
,973
,013
,000
,947
,998
Dewailly et al., Hum Reprod, 2011, 26:3123-9
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PRECONGRESS COURSE 07 I BARCELONA, SPAIN – 1 JULY 2018 81