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Eating behaviour and body image
• Eating disorders (ED)
• Anorexia nervosa (AN)
• Bulimia nervosa (BN)
• Binge eating disorder (BED) • Night eating syndrome (NES)
• PCOS present more often with ED even after adjusting for BMI • High prevalence 12-21% vs. 3-4% in controls Månsson et al., 2008
• Concern about weight: 32% vs 10% Lee et al., 2017
• IncreasedriskforBN(OR1.21CL1.03-1.41)Cestaetal.,2016
• BingeeatingwasassociatedwithhighBMI,foodcravings,emotionaleating,uncontrolledeating
• EDhasbeenassociatedwithdepressionandanxiety
• Body image disturbances are also prevalent and they seem to associate with depression
Pastore et al., J Psychosom Res 2011, Livadas et al., Cin Endo 2011, Larsson et al., Clin Nut 2016, Lee et al., Fertility and Sterility 2017
Jeanes et al., 2016
Mechanism of mental distress in PCOS
• Hyperandrogenism?
• DHT-induced PCOS-micedepression and anxiety-like behavior
• Manti et al., FASEB 2018 • Yu et al, Bio Reprod 2016
• Autonomous nervous system and decreased HRV?
• Alvares et al., J Psychiatry Neurosci. 2016 (general population)
• Inflammation?
• Chamberline Br J Psychiatry. 2018 (general population)
• Bauer and Teixeira, Ann N Y Acad Sci. 2018 (general population)
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