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Improved Live Birth Rates with elective FET in PCOS
 Increased rate ratio of Live birth with initial eFET: 1.17 (95% confidence interval, 1.05 to 1.31; P = 0.004).
 Similar cumulative pregnancy rates after 12 months follow- up from initial transfer
FET is effective!!
Chen et al, NEJM 2016
Mixed Risk Benefit of Frozen vs Fresh Embryo Transfer
Benefit
 Lower rate of pregnancy loss (22.0% vs 32.7%)
– Rate ratio of 0.67 (95% CI, 0.54 to 0.83; P<0.001), and of the ovarian
 Marked reduction in OHSS (1.3% vs. 7.1%)
Rate ratio of 0.19 (95% CI, 0.10to 0.37); P<0.001,
Risk
 Higher rate of preeclampsia (4.4% vs. 1.4%)
 Rate ratio of 3.12 (95% CI, 1.26 to 7.73); P = 0.009
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