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Animal models
Controls: 20% protein
Undernourished: 8% protein
715 days 765 days
517 days
568 days
Ozanne, Nature 2004
8
Page 54 of 135
8
Conclusion
Animal evidence that in utero exposure to undernutrition leads
- Cardiovascular disease
- Increased blood pressure
- Increased stress response
- Decreased nephron endowment
- Increased obesity
- Impaired glucose metabolism
- ....
- Shorter life span
What about the effects in humans?
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PresentationAMC.pptx PresentationAMC.pptx