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P-662 Incidental identi cation of copy number variations (CNV) in patients during preimplantation genetic diagnosis (PGD) – clinical implications and counseling issues when encountering secondary ndings
R. Cabey1, D. Goldberg-Strassler2, E. Armenti2, A. Jordan2, J. Gay2, M. Konstantinidis3,
R. Prates4, S. Munne5
1Reprogenetics, genetic counseling, Livingston- New Jersey, U.S.A. 2Reprogenetics, genetic counseling, Livingston- NJ, U.S.A. 3Reprogenetics, molecular, Livingston- NJ, U.S.A.
4Reprogenetics, molecular, Miami- FL, U.S.A.
5Reprogenetics, genomics research, Livingstion- NJ, U.S.A.
P-663 Day of trophectoderm biopsy in uences implantation and ongoing pregnancy rates of similarly-graded euploid blastocysts
M. Irani1, C. O'Neill1, G. Palermo1, G. Vinay1, C. Zhang1, X. Qin1, K. Xu1, N. Zaninovic1, Z. Rosenwaks1
1Weill Cornell Medicine, The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, New York, U.S.A.
P-664 PGS is most bene cial for older women with many embryos
E. Fedorova1, S. Shlykova2, K. Shunkina1, O. Zaitceva3, E. Lapina4, T. Yanchuk4, A. Kalugina4 1AVA-PETER Ltd., Genetics, Saint-Petersburg, Russia C.I.S.
2AVA-PETER Ltd., Embryology, Saint-Petersburg, Russia C.I.S.
3AVA-PETER Ltd., Reproductology, Saint-Petersburg, Russia C.I.S.
4AVA-PETER, Reproductology, Saint-Petersburg, Russia C.I.S.
P-665 Intermediate number of CGG repeats in patients with Fragile X premutation is associated with poorer ovarian reserve
J. Lekovic1, L. Man2, N. Pereira2, K.P. Xu2, Z. Rosenwaks2, J. Gerhardt2
1Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine- Weill Cornell Medicine, Obstetrics and Gynecology, New York City- NY, U.S.A.
2Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine- Weill Cornell Medicine, Obstetrics and Gynecology, New York, U.S.A.
P-666 Re ning embryo transfer strategies after PGD for translocations using comprehensive chromo- some testing
E. Coonen1,2, C. Van Uum1, Engelen. J.1, M. Meijer-Hoogeveen3, R. Van Golde2, J. Derhaag2, A. Van Montfoort1, M. Pieters3, M. Goddijn4, J. Brink-van Der Vlugt5, S. Repping4,
C. De Die-Smulders1, S. Mastenbroek4
1Department of Clinical Genetics, GROW School for Oncology and Developmental Biology Maastricht University Medical Center+, Maastricht, The Netherlands
2Center for Reproductive Medicine, GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre+
3Department of Reproductive Medicine, University Medical Center Utrecht, Utrecht, The Netherlands 4Center for Reproductive Medicine, Academic Medical Centre, University of Amsterdam
5Center for Reproductive Medicine, University Medical Center Groningen, Groningen, The Netherlands
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