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Differences in Composition of different u-FSH & r-FSH preparations
(Lombardi et al., Electrophoresis 2013)
Differences in Composition of different FSH preparations
(Lombardi et al., Electrophoresis 2013; Yding Andersen, Reprod Biomed Online 2004)
Complexity of different commercially available FSH preparations
50 45 40 35 30 25 20 15 10
5
FSH isoform distribution amongst different commercially available preparations
00
Asialoglycan Monosialylated Disialylatad Trisialylated Tetrasialylated Fostimon Gonal-F Purgeon
Metrodin
Metrodin HP pI < 4 (%)
Puregon pI > 4 (%)
Gonal-F
100
90
80
70
60
50
40
30
20
10
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PRECONGRESS COURSE 06 I GENEVA, SWITZERLAND – 2 JULY 2017 27
Fostimon
Gonal F
Puregon
