Page 20 - PRECONGRESS COURSE 06

Learning Objectives
 Provide some understanding of the differences between FSH molecules throughout the menstrual cycle, and throughout a woman’s reproductive life span and during her postmenopausal years
 Introduce the concept of FSH isoforms and their implications in vitro as well as in vivo in terms of follicular and endocrine responses
 Discuss some pharmacodynamics of urinary and recombinant FSH preparations
 Discuss some pharmacogenomic aspects of single nucleotide polymorphisms in the FSH-β chain
and the FSH receptor
 Provide some understanding if and how these differences might affect clinical outcome of COH in IVF cycles
 Conclude with some take home messages
ESHRE PCC 6:
Ovarian Stimulation for IVF: Individualization and beyond:
The stimulation drug FSH: What do we need to know?
PHYSIOLOGY:
DIFFERENT ISOFORMS OF FSH
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