Page 164 - PRECONGRESS COURSE 06

Evidence from animal studies Primary follicle development
IGF1/IGFR production
Vendola et al., Biol Reprod 1999
Weak evidence from human studies
 Preliminary uncontrolled and small RCTs
 Treatment with testosterone
1. May increase AFC
2. May increase the number of growing follicles
3. May increase pregnancy rates
Balasch et al., Hum Reprod 2006 Fabregues et al., Hum Reprod 2009
164
Page 160 of 258