Page 90 - PRECONGRESS COURSE 04

Learning objectives
1) To be able to cite the major developments in endometrial receptivity biomarker development
2) To discuss the causes of implantation failure and endometrial receptivity defects
3) To understand the concept of progesterone resistance and estrogen dominance associated with endometriosis
4) To appreciate different approaches for improving endometrial receptivity and pregnancy outcomes
The Endometrium
Dependent on sex steroids ◦ Estrogenandprogesterone
Undergoes cyclic development
Becomes receptive for pregnancy
Is prone to imbalance due to: ◦ Dependenceoninflammation ◦ Leukocyteinfiltration
◦ Immunefunction
◦ Intrinsicpathologies ◦ Hydrosalpinx
◦ Fibroids/polyps
◦ Adenomyosis
◦ Endometriosis
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