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Dual role for Myosin Vb
• Generating a non-specific pressure gradient that triggers centering
• Generating sustained cytoplasmic activity that allows fluidization of the cytoplasm, making it compatible with the movement of a large object
Almonacid NCB 2015
Why centre chromosomes to put them off-centre afterwards?
Oocyte growth Meiotic divisions
Immature Oocyte oocyte
Fertilization
Embryo
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PRECONGRESS COURSE 03 I GENEVA, SWITZERLAND – 2 JULY 2017 49
