Page 53 - PRECONGRESS COURSE 01

Total motile sperm count: a better indicator for the severity of male factor infertility than the WHO sperm classification system
longitudinal cohort study
unselected infertile couples referred to 3Dutch hospitals Period: Jan 2002 – Dec 2006.
N = 2476 infertile couples
Inclusion criteria: only couples with male infertility as a single diagnosis or unexplained infertility
follow-up period of 3 years.
J.A.M. Hamilton et al. Hum. Reprod. 2015;30:1110-1121
© The Author 2015. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com
Predictive value of sperm morphology and progressively motile sperm count for pregnancy outcomes in IUI
Lemmens et al, Fertil Steril 2016;105:1462-8 Retrospective – 4251 IUI cycles
Variable
No.
First IUI cycle OR (95% CI)
First IUI episode OR (95% CI)
Sperm morphology
≤4%
444
1.19 (0.80–1.79)
1.39 (1.06–1.81)
>4%
629
1.00 (Ref)
1.00 (Ref)
TPMSC
≤20 million
297
0.86 (0.51–1.45)
1.02 (0.73–1.44)
20–50 million
219
0.92 (0.53–1.61)
1.14 (0.78–1.65)
50–100 million
223
0.77 (0.43–1.38)
0.85 (0.58–1.24)
>100 million
333
1.00 (Ref)
1.00 (Ref)
NIPMS
≤1 million
103
0.67 (0.30–1.51)
0.42 (0.23–0.76)
1–5 million
236
1.05 (0.64–1.71)
1.13 (0.81–1.57)
5–10 million
171
1.02 (0.58–1.79)
1.73 (1.21–2.46)
>10 million
655
1.00 (Ref)
1.00 (Ref)
Age (per y)
Female
1,166
0.93 (0.89–0.98)
0.91 (0.88–0.94)
Male
1,166
0.96 (0.92–1.00)
0.95 (0.92–0.97)
No. of cycles in episode (per cycle)
1,166
NA
0.79 (0.74–0.85)
Page 49 of 175
PRECONGRESS COURSE 01 I GENEVA, SWITZERLAND – 2 JULY 2017 53