Page 41 - PRECONGRESS COURSE 01

Individual prediction is impossible
Concentration Total Count (M) Motility (A+B) morphology
fertile median range
47.5 1-215 125.0 2-545 57.5 0-85 12.0 1-27
subfertile median range
21.0 0-141 62.0 0-551 48.5 0-85 6.0 0-18
Ombelet et al., Hum. Reprod.1997: 144 fertile men vs 143 subfertile men
Biochemical versus light microscopy
Area under ROC (%)
• Morfology 73.5
• Concentration 65.6
• HOS 65.6
• Total Count 63.2
• Hepatocyte Growth Factor 61.9
• Total Motility 61.6
• Inhibin B 59.3
• Interleukin 1‐alpha 58.8
• Xanthine Oxydase 58.3
• Transferrin 58.3
• Clara Cell Protein (CC 16) 55.5
• Interleukin 7 54.7
• LIF receptor 53.5
• Alpha‐glucosidase 50.2
Page 37 of 175
PRECONGRESS COURSE 01 I GENEVA, SWITZERLAND – 2 JULY 2017 41