Page 31 - FINAL PROGRAM

PRECONGRESS COURSE 09
Sunday, 3 July 2016 I Hall 3 C
Genetics and epigenetics behind subfertility and reproductive system disease Organised by the Special Interest Group Reproductive Genetics
COURSE COORDINATORS
Ursula Eichenlaub-Ritter (Germany) and Claudia Spits (Belgium)
COURSE DESCRIPTION
Knowledge on epigenetic and genetic mechanisms behind male and female subfertility and on new approaches to identify disease affecting reproduction has dramatically increased in the last years. Thus, information on
the relevance of epigenetic disturbances in male subfertility, origin of chromosome instability in oocytes and embryos, and on new ways to detect pathways and epigenetics in reproductive pathologies should be provided to all involved in ART, human genetics, and human reproduction. The course is therefore aimed at covering novel developments, and their potential applications in genetics and epigenetics in male and female subfertility and (epi)genetic disease. The course should bridge the gap between basic research and clinical applications.
TARGET AUDIENCE
Professionals working in ART and in human reproductive medicine, in particular in reproductive genetics, as well as clinicians from different elds, embryologists, lab technicians, and basic scientists in reproduction.
EDUCATIONAL NEEDS AND EXPECTED OUTCOMES
The rapid developments in genetics and epigenetics in reproduction necessitate that ESHRE provides updated information on the eld and in the clinics to bridge basic sciences with clinical application. The information provided in the course should increase the knowledge on the basis of subfertility by epimutation and chromosomal instability in germ cell formation, provide information on recent advances in methodologies to identify risks and advance personalized medicine for clinicians, embryologists and geneticists in reproductive medicine.
09:00 - 09:05 Introduction – Ursula Eichenlaub-Ritter (Germany) SESSION I: EPIGENETICS BEHIND MALE INFERTILITY
09:05 - 09:25
09:35 – 09:50 09:50 - 10:20 10:20 - 10:30 10:30 - 11:00
Epigenetic alterations in sperm DNA associated with testicular cancer treatment - relevance for male fertility – Jacquetta Trasler (Canada)
Discussion
Epigenetics in male infertility: Challenges for andrology – Jörg Gromoll (Germany) Discussion
Coffee break
SESSION II: EPIGENETIC AND GENETIC ELEMENTS BEHIND CHROMOSOME INSTABILITY IN OOCYTES AND EMBRYOS
11:00 - 11:30 11:30 - 11:45 11:45 - 12:15 12:15 - 12:30 12:30 - 13:30
Chromothrypsis and genome instability in human reproduction – Franck Pellestor (France) Discussion
Epigenetic basis of oocyte aneuploidy: mechanisms in meiosis I – Keith Jones (United Kingdom) Discussion
Lunch break
FINAL PROGRAMME I HELSINKI, FINLAND – 3 TO 6 JULY 2016 27
PRECONGRESS COURSES